A new study published in the journal of the American Diabetes Association has revealed a significant association between real-world weight loss and a reduced risk of obesity-related cancers.
Conducted by researchers including Kenda Alkwatli, MD, Clinical Fellow at Cleveland Clinic, the study involved 172 participants, with 100,143 in the control group and 5,329 cases examined.
The participants had a median body mass index (BMI) at censoring of 34.2 for cases and 34.5 for controls, indicating obesity as defined by the US-based Centers for Disease Control and Prevention (CDC).
Using logistic regression models, the study assessed the impact of BMI changes over three, five, and 10-year intervals preceding cancer diagnosis in cases compared to controls.
The findings indicated a notable reduction in the risk of several types of cancer associated with obesity.
Specifically, the study highlighted reduced risks for renal cell carcinoma over three years, multiple myeloma over 10 years, and endometrial cancer over three and five years among primary cancer endpoints.
As per IANS, Dr. Kenda Alkwatli emphasized the significance of these findings.
She stated, “This study reinforces how crucial it is to treat obesity as a chronic disease.”
Meanwhile, she expressed hope that these findings would guide researchers in effectively using weight loss to address comorbidities, including cancer, in obese patients.
According to the researchers, obesity is known to increase the risk of at least 13 types of cancer, attributed to factors such as excess estrogen and elevated insulin.
These cancers include breast, kidney, ovary, liver, and pancreatic cancer.
The study underscores the importance of weight management as a critical factor in reducing the risk of obesity-related cancers, offering insights into potential strategies for cancer prevention and management among individuals struggling with obesity.
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